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This site provides biochemical methods and computer tools to allow students to use their own DNA "fingerprints" as a starting point in the study of human evolution. Two experiments are currently available, which are supported by reagents and ready-to-use kits available from Carolina Biological Supply Company. |
CLICK ON ONE EXPERIMENT TO BEGIN: |
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Mitochondrial (mt) Point Mutations are single nucleotide polymorphisms (SNPs) detected in the ring-shaped chromosome found in the cell's energy-producing organelle. Mutations are common in mt DNA, in large part due to exposure to oxygen free radicals generated as a by-product of respiration. Mitochondrial mutations can be used to retrace the common maternal lineage of modern humans and to determine our relationship to the extinct hominid Neandertal. |
Alu
Insertion Polymorphism detects the presence
or absence of a "jumping gene" on chromosome 16. This simple genetic system
has only two alleles and three genotypes. Despite this simplicity, allele
frequencies vary greatly in different world populations. Alternate explanations
about the causes of this variation are consistent with opposing theories
of the origins of modern humans.
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